Alexey Shaitan
- Research Fellow:Faculty of Computer Science / AI and Digital Science Institute / International Laboratory of Bioinformatics
- Alexey Shaitan has been at HSE University since 2021.
Education and Degrees
- 2010
Candidate of Sciences* (PhD)
- 2007
Degree in Condensed Matter Physics
Lomonosov Moscow State University
According to the International Standard Classification of Education (ISCED) 2011, Candidate of Sciences belongs to ISCED level 8 - "doctoral or equivalent", together with PhD, DPhil, D.Lit, D.Sc, LL.D, Doctorate or similar. Candidate of Sciences allows its holders to reach the level of the Associate Professor.
Courses (2023/2024)
- Molecular Modeling (Master’s programme; Faculty of Computer Science; 2 year, 1, 2 module)Rus
- Past Courses
Publications13
- Article Shaitan A., Комарова Г. А., Timokhin G., Грибкова А. К., Алексеев В. И., Бигильдеев А. Е. The Role of Changes in Structure and Dynamics of Chromatin due to COVID-19 / Пер. с рус. // Russian Journal of Genetics. 2024. Vol. 60. No. 1. P. 11-31. doi (in press)
- Chapter Alekseev K., Poptsova M., Shaitan A. High-throughput computational design of protein binders for complex targets using deep learning models, in: Proceedings of 11th Moscow Conference on Computational Molecular Biology MCCMB'23. IITP RAS, 2023.
- Article Nikita A. Kosarim, Armeev G. A., Alexey K. Shaytan, Kirpichnikov M. P. Analysis of Ion Atmosphere Around Nucleosomes Using Supercomputer MD Simulations // Supercomputing Frontiers and Innovations. 2022. Vol. 9. No. 2. P. 56-67. doi
- Article Sivkina A., Karlova M., McCullough L., Formosa T., Shaitan A., Feofanov A., Kirpichnikov M., Sokolova O., Studitsky V. Electron microscopy analysis of ATP-independent nucleosome unfolding by FACT // Communications Biology. 2022. Vol. 5. No. 1. Article 2. doi
- Article Shaitan A., Novikov R., Vinnikov R., Gribkova A., Glukhov G. From DNA-protein interactions to the genetic circuit design using CRISPR-dCas systems // Frontiers in Molecular Biosciences. 2022. Vol. 9. Article 1070526.
- Article Armeev G., Gribkova A., Shaitan A. Nucleosomes and their complexes in the cryoEM era: Trends and limitations // Frontiers in Molecular Biosciences. 2022. Vol. 9. Article 1070489. doi
- Article Armeev G., Kniazeva A., Komarova G., Kirpichnikov M., Shaytan A. Histone dynamics mediate DNA unwrapping and sliding in nucleosomes // Nature Communications. 2021. Vol. 12. Article 2387. doi
- Article Espiritu D., Gribkova A., Gupta S., Shaytan A., Panchenko A. Molecular Mechanisms of Oncogenesis through the Lens of Nucleosomes and Histones // Journal of Physical Chemistry B. 2021. Vol. 125. No. 16. P. 3963-3976. doi
- Article Novikov R., Armeev G., Gribkova A., Kacher J., Gluhov G., Shaitan A. Detecting Cas9-sgRNA Complex Interactions with DNA via Fluorescent Microscopy: Computer Simulations of Experimental Designs // Microscopy and Microanalysis. 2020. Vol. 26. No. S2. P. 310-311. doi
- Article Armeev G., Panchenko A., Feofanov A., Shaitan A. Integrative Modeling of Nucleosomes and Supranucleosomal Structures // Biophysical Journal. 2020. Vol. 118. No. 3S1. Article 318-Pos. doi
- Article Hada A., Hota S., Luo J., Lin Y., Kale S., Shaitan A., Bhardwaj S., Persinger J., Ranish J., Panchenko A., Bartholomew B. Histone Octamer Structure Is Altered Early in ISW2 ATP-Dependent Nucleosome Remodeling // Cell Reports. 2019. Vol. 28. No. 1. P. 282-294. doi
- Article Армеев Г. А., Грибкова А. К., Поспелова Ю., Комарова Г. А., Shaitan A. Linking chromatin composition and structural dynamics at the nucleosome level // Current Opinion in Structural Biology. 2019. Vol. 56. P. 46-55. doi
- Article Shaitan A., Xiao H., Armeev G. A., Gaykalova D. A., Komarova G. A., Wu C., Studitsky V. M., Panchenko A. R. Structural interpretation of DNA-protein hydroxyl-radical footprinting experiments with high resolution using HYDROID // Nature Protocols. 2018. Vol. 13. No. 1. P. 2535-2556. doi
Employment history
02.2021- |
Research fellow |
Bioinformatics Lab, HSE University | |
2013-2017 |
Visiting Fellow |
National center for biotechnology information, National institutes of health, USA | |
2012- |
Leading research fellow |
Moscow State University, Faculty of Biology, Department of Bioengineering | |
2010-2012 |
Research fellow |
Moscow State University, Faculty of Biology, Department of Bioengineering; focus on computer simulations of bio and nano structures | |
2008-2010 |
Leading engineer |
Moscow State University, Faculty of Biology, Department of Bioengineering; focus on IT infrastructure for computer simulations | |
2009-2011 |
Research fellow |
University of Ulm, Institute of Polymer Science, director Prof. A.R. Khokhlov, Ulm, Germany | |
2006-2008 |
Teacher |
School N1326/Lyceum 1586, subjects: computer modeling (10-11 grades), computer methods in biology and physics (7-9 grades) |
Russian Conference "VII Congress of Biophysicists of Russia" April 17-23, 2023, Krasnodar
The International Bioinformatics Laboratory took part in the Conference "VII Congress of Biophysicists of Russia" on 17-23 April 2023 in Krasnodar based on the Kuban State Technological University
International Conference "Multiscale DNA Modelling from Electrons to Nucleosomes: 22 Years of the Ascona B-DNA Consortium", 16-21 April 2023
A member of the International Bioinformatics Laboratory participated in the International Conference "Multiscale DNA modelling from electrons to nucleosomes: 22 years of the Ascona B-DNA Consortium" in Ascona, Switzerland. The conference was held on 16-21 April 2023
School "Genetics and Epigenetics: Mechanisms, Structure, Function" at the Biology Department of Moscow State University, October 29-30, 2022
The International Laboratory of Bioinformatics participated in the School for young scientists "Genetics and Epigenetics: Mechanisms, Structure, Function" which was held at the Biology Department of Lomonosov Moscow State University from October 29 to 30, 2022.
HSE University Staff Members Elected to the Russian Academy of Sciences
The results of the vote were announced at the General Assembly of the Russian Academy of Sciences (RAS), which took place from June 1-3. The newly elected Members and Corresponding Members of the RAS include eight scholars from HSE University.
The Moscow Conference on Computational Molecular Biology (MCCMB) 07/30/2021 - 08/02/2021
The Moscow Conference on Computational Molecular Biology (MCCMB) took place on 07/30/2021 - 08/02/2021